What Medications Are Used in Medication-Assisted Therapy?
The Food and Drug Administration (FDA) has approved several medications for the treatment of both opioid use disorders and alcohol use disorders.
To treat OUD, the following medications have been approved:²
Buprenorphine: Buprenorphine helps to reduce opioid cravings.
Naltrexone: Naltrexone stops feelings of euphoria because of opioid use by blocking the sedative effects of opioids on the brain.
Methadone: Methadone works in many ways. It limits the effects of opioids while simultaneously decreasing cravings and withdrawal symptoms.
Sublocade: Sublocade was approved in 2017 to treat moderate to severe opioid use disorder, and it is a monthly buprenorphine injection; it is the first once-a-month injection approved by the FDA.³
The FDA has approved the following medications to treat AUD:
Naltrexone: Also used in the treatment of OUD; Naltrexone prevents feelings of euphoria and sedation, which can help prevent relapse and support treatment participation and engagement.
Disulfiram: Disulfiram is appropriate to use after withdrawal has occurred and you are free from alcohol; when you consume alcohol on disulfiram, you can experience nausea, vomiting, headache, and difficulty breathing. Disulfiram creates an aversion to alcohol, reducing your desire for it due to the side effects that will occur if you consume it.
Acamprosate: Like disulfiram, acamprosate should be taken after detox has been completed and you are sober and want to maintain your sobriety.² Acamprosate does not impact your withdrawal symptoms; however, it does reduce your cravings for alcohol.³
Behavioral Therapies in MAT
Federal law requires that individuals enrolled in an opioid treatment program (OTP) who are receiving Medication-assisted therapy in Phoenix, AZ are obligated to attend counseling.² Additional services may be included in your treatment plan, along with MAT, including legal and housing assistance, and employment services.²
Therapy can be conducted in individual and group settings. Common behavioral therapy treatments used in MAT include:⁴
- Cognitive-behavioral therapy (CBT)
- Community reinforcement approach
- Motivational interviewing
- Contingency management